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Finasteride oral tablet is used for the treatment of male pattern hair loss by inducing apoptosis of keratinocytes in the hair follicle. It is an enzyme modulators that increase the activity of a specific enzyme called Nrf2 that can increase hair follicular regeneration. 5.2. Effects on Female finasteride quarter tablet Reproductive Health: The major mechanism of action Finasteride is to reduce androgen levels and improve sexual function in men. This is seen two ways: (1) a reduction of DHT concentration in the skin; (2) a reduction of vaginal secretion and a reduction of pregnancy rates Price of generic topamax (Rasch, 2001). The decrease finasterid ct 5 mg filmtabletten in DHT concentration skin is due to the inhibition of tyrosine hydroxylase (TH), the enzyme that makes testosterone. In addition, Finasteride inhibits the reuptake of finasteride tablet size 5α-reductase, thereby suppressing the activity of LH and testosterone within the uterus (Deutsch, 2000). Finasteride can also have a direct effect on the female reproductive tract and fertility issues in women. It does this by decreasing sperm production and count. For example, the female reproductive tract is highly sensitive to the effects of DHT on sperm production. The loss of a testis causes 50-70% reduction of spermatogenesis within 3-5 months (Rasch, 2001). Another way this can occur is when one or more types of male hormones interfere with the functioning of sex steroids (Welker et al., 2001; Sánchez 2001). For example, estrogen inhibits the secretion of gonadotropin-releasing hormone (GGRHR) and luteinizing from the anterior pituitary gland, both of which are responsible for inhibiting the secretion of DHT. In addition, estrogen inhibits the secretion of gonadotropin-interacting steroid (GnRH) and follicle stimulating hormone (FSH). The effect of these two hormones is to block the effect of DHT and cause a further drop in spermatogenesis. The effect of finasteride on luteinizing hormone levels can also be blocked by co-administration of the female sex steroid progesterone, since progesterone increases the synthesis of LH and FSH (Das, 2010). There are some notable instances of sexual dysfunction in the female reproductive tract that have been reported. In one such instance, female pattern hair loss was not associated with an increase in serum estradiol level, although an increase in progesterone levels online pharmacy programs in canada was a possible cause (Rasch, 2001). However, the decrease in DHT concentration skin (and decrease in the number of mature testes) is consistent with a possible interaction between DHT and the GnRH receptor (González de los Reyes, 1999). Further studies are required to elucidate this issue further.

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